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Of all the causes of hair loss, androgenic alopecia accounts for about 95%. There are already several treatments for androgenic alopecia. However, patients who know androgenic alopecia already know that androgenic alopecia often requires a combination of treatments with many different modes of action. Of the many ways to treat androgenic alopecia, what is the best solution?
Androgenic alopecia cause by DHT (dihydrotestosterone), so needs to reduce the DHT level first to prevent further hair loss, and the hair density will gradually recover after the hair loss stops. Finasteride is the first oral drug approve by the FDA to treat hair loss by reducing DHT levels. There are other drugs with similar effects, such as oral Dutasteride, topical Ru58841, topical CB-03-01, topical KX-826, etc.
Once the hair loss process has stopped, the next step is how to promote hair growth. This is where Minoxidil comes into play. Minoxidil delivers nutrients to the hair follicles by a variety of known and unknown means, promoting the growth of growing hair and resulting in denser, better hair. Other drugs that promote hair growth are WAY316606, SM04554 and Pyrrolidinyl Diaminopyrimidine oxide.
The treatment period for hair loss is very long. In the process of treating hair loss, the use of shampoo has a great impact on the hair. If you choose a shampoo that is irritating to the scalp, it will affect the treatment process of hair loss. Therefore, the right shampoo is important for patients who are treating hair loss. In this process, shampoos containing Ketoconazole and Pyrrolidinyl Diaminopyrimidine oxide are commonly used. Hair loss medications such as Minoxidil have a certain irritating effect on the scalp and may cause dry, itchy, redness, etc. Choosing the right shampoo will help relieve these sides.
Therefore, the standard treatment combination for androgenic alopecia can be: Finasteride + Minoxidil + Pyrrolidinyl. However, every drug may not work for everyone. If you stack these drugs on top of each other at the beginning of treatment, you may have all three of them working, you may have only two of them working, you may even have only one of them working. Therefore, at the beginning of treatment, one drug alone should be used to see if it works for you. And then combine them.
In the treatment of hair loss, some people also add Microneeding. Microneeding to help the absorption of topical drugs, promote hair growth. Some studies show that when combine microneedles with Minoxidil, they are more effective in treating hair loss than Minoxidil alone. Therefore, the best solution for androgenic alopecia is Finasteride + Minoxidil + Pyrrolidinyl + Microneeding.